Cagrilintide dosage and reconstitution
A weekly fullness shot that stacks on a GLP-1 when the weight stalls. Strong in trials, strong on nausea; start tiny.
UnderstandWhat it isApplyHow to use it
Staying safe
Things people sometimes notice
- Nausea, worst in the week after a dose increase and after eating past the fullness
- Eating noticeably less without trying, which is the effect
- Constipation, or the opposite, as the stomach adjusts
- Tiredness in the first few weeks, usually from eating less
Stop and get help if (trouble breathing or swelling: call 911)
- Severe or constant stomach pain, especially spreading to the back, a pancreatitis warning
- Vomiting that keeps you from holding down fluids
- Hives or swelling of the face or lips
Talk to your doctor first, especially if
- You have had pancreatitis, because amylin and GLP-1 drugs are both flagged for it
- You take insulin or sulfonylureas, since eating much less can drop your blood sugar too far
- You have gastroparesis or a slow stomach, which the combination with a GLP-1 can make worse
- You are pregnant, nursing or trying to be; there is no data and the trials excluded you
Mixing it
Works on the amylin receptor, not the GLP-1 pathway, it curbs appetite centrally rather than slowing gastric emptying, which is why it pairs well with a GLP-1. Start very, very low.
Bring the vial to room temperature and clean the top.
Add bacteriostatic water per your vial size and confirm with the calculator.
Swirl gently, do not shake.
Inject once a week and step the dose up slowly.
Store in the fridge per the label.
The short version
What it isA weekly fullness shot that stacks on a GLP-1 when the weight stalls. Strong in trials, strong on nausea; start tiny.
EvidenceAnimal 4/5 · Human 3/5 · Not approved
Want the background?What it is and the research
This is education, not medical advice. Doses shown are the patterns people commonly follow, not a prescription. Talk with a doctor before starting, especially if you take other medicines or have a health condition.