LL-37 dosage and reconstitution
Your body's own antimicrobial peptide, for stubborn wounds, chronic infections and biofilm. Start at 50 mcg; more is not better here.
UnderstandWhat it isApplyHow to use it
Staying safe
Things people sometimes notice
- Redness or itch at the injection site, more at higher doses
- A warm flush shortly after a dose
- A short flare of fatigue, achiness or looser stools in the first week when treating a chronic infection
Stop and get help if (trouble breathing or swelling: call 911)
- Hives, swelling of the face or trouble breathing (histamine-type reactions happen with this one)
- Joint pain, a new rash or plaques, or any autoimmune symptom flaring
- Fever, spreading redness or pus around a wound, which means you need antibiotics, not more peptide
Talk to your doctor first, especially if
- You have an autoimmune disease (lupus, psoriasis, rheumatoid arthritis, rosacea); LL-37 is implicated in flares of these
- You take immunosuppressants or biologics; it modulates the same immune pathways
- You have an active infection with fever; it is not a substitute for antibiotics
- You are pregnant or nursing; no data
Mixing it
Here is the math for a 5 mg vial mixed with 2 ml of bacteriostatic water.
Let the vial reach room temperature and wipe both vial tops with an alcohol swab.
Draw 2 ml of bacteriostatic water into the syringe.
Push the water in slowly against the side of the glass, not onto the powder.
Swirl gently until dissolved, do not shake.
Store it in the fridge. Once mixed it stays good for about 3 to 4 weeks.
The short version
What it isYour body's own antimicrobial peptide, for stubborn wounds, chronic infections and biofilm. Start at 50 mcg; more is not better here.
EvidenceAnimal 3/5 · Human 2/5 · Not approved
Want the background?What it is and the research
This is education, not medical advice. Doses shown are the patterns people commonly follow, not a prescription. Talk with a doctor before starting, especially if you take other medicines or have a health condition.