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Skin & HairVitality & HormonesHigher Risk

Melanotan II dosage and reconstitution

A deep tan from a few tiny shots a week, with a libido kick thrown in. Potent, so you start at 100 mcg and respect your moles.

UnderstandWhat it isApplyHow to use it

Staying safe

Things people sometimes notice

  • Nausea and a hot flush in the first hour, worst on the first few doses and at higher doses; dosing at bedtime hides most of it
  • Freckles and moles darkening, and uneven darkening on the face in the first weeks
  • Spontaneous erections in men, usually in the hours after a dose
  • Less appetite, and tiredness or yawning after a dose for some

Stop and get help if (trouble breathing or swelling: call 911)

  • A mole that changes shape, size, color or border, or a new dark spot that is not a freckle; get it checked before another dose
  • An erection lasting more than a few hours; that is a medical emergency, not something to wait out
  • Vomiting, fainting, a pounding headache or a blood pressure reading well above your normal
  • Rash, hives, swelling or trouble breathing

Talk to your doctor first, especially if

  • You have many moles, an atypical mole, or any personal or family history of melanoma, because it darkens moles and nobody has shown that is harmless; get a skin check first
  • You have high blood pressure or a heart condition, since it raises blood pressure for hours after a dose
  • You take blood pressure medicines or erectile dysfunction drugs, because the effects stack

Mixing it

Here is the math for a 10 mg vial mixed with 3 ml of bacteriostatic water, taking a 100 mcg starting dose.

Bring the vial to room temperature and clean the top.

Add 3 ml of bacteriostatic water slowly.

Swirl gently, do not shake.

Start very low, since nausea and other effects are dose-related.

Store in the fridge. Use within about 3 to 4 weeks once mixed.

The short version

What it isA deep tan from a few tiny shots a week, with a libido kick thrown in. Potent, so you start at 100 mcg and respect your moles.
EvidenceAnimal 3/5 · Human 2/5 · Not approved
Want the background?What it is and the research
This is education, not medical advice. Doses shown are the patterns people commonly follow, not a prescription. Talk with a doctor before starting, especially if you take other medicines or have a health condition.
© 2026 PeptideHelp. This platform is for educational purposes only.
Melanotan II dosage, reconstitution & schedule · PeptideHelp