HNG (S14G-Humanin) dosage and reconstitution
The lab-strength version of humanin, a cell-survival signal your mitochondria make. Brain and heart protection in rodents only.
UnderstandWhat it isApplyHow to use it
Staying safe
Things people sometimes notice
- Redness or a small lump at the injection site
- Nothing systemic reported consistently; side effects in people are essentially uncharacterized
- Mild tiredness or sleep changes in the first week, reported by some and unverified
Stop and get help if (trouble breathing or swelling: call 911)
- Hives, swelling of the face or lips, or trouble breathing
- Shakiness, sweating or confusion that looks like low blood sugar, especially if you take diabetes medicine
- A new lump, unexplained weight loss or night sweats; a peptide that keeps stressed cells alive is not the thing to continue while that is checked
Talk to your doctor first, especially if
- You have any cancer history or an unexplained mass. HNG's core effect is blocking cell death, which is the opposite of what you want near a tumor
- You take insulin or sulfonylureas, since rodent data shows effects on insulin sensitivity and lows are possible
- You take hormone therapy, fertility drugs or growth-hormone peptides; humanin interacts with the IGF-1 axis in animal work and nobody has studied the mix
- You are pregnant, nursing or trying to be; no data
Mixing it
HNG comes as a dry powder you mix with bacteriostatic water. Here is the math for a 5 mg vial mixed with 1 ml: 5 mg/ml, so one unit on a U-100 syringe is 50 mcg and a 250 mcg dose is a 5-unit draw.
Let the vial reach room temperature and wipe both tops with an alcohol swab.
Add 1 ml of bacteriostatic water slowly, aimed at the glass. Swirl, do not shake.
Draw on a U-100 insulin syringe: 2 units = 100 mcg, 5 units = 250 mcg, 10 units = 500 mcg.
Store in the fridge and use within about 4 weeks once mixed.
Keep any trial short given the lack of human safety data.
The short version
What it isThe lab-strength version of humanin, a cell-survival signal your mitochondria make. Brain and heart protection in rodents only.
EvidenceAnimal 3/5 · Human 0/5 · Not approved
Want the background?What it is and the research
This is education, not medical advice. Doses shown are the patterns people commonly follow, not a prescription. Talk with a doctor before starting, especially if you take other medicines or have a health condition.